ACT-NOW Implementation Guide
0.5.0 - ci-build NZ

ACT-NOW Implementation Guide - Local Development build (v0.5.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

: Dose adjustment reason - TTL Representation

Draft as of 2026-06-15

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:ValueSet ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "an-dose-adjustment-reason"] ; # 
  fhir:text [
fhir:status [ fhir:v "generated" ] ;
fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet an-dose-adjustment-reason</b></p><a name=\"an-dose-adjustment-reason\"> </a><a name=\"hcan-dose-adjustment-reason\"> </a><ul><li>Include these codes as defined in <code>http://snomed.info/sct/21000210109</code><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td>271737000</td><td>Anaemia</td></tr><tr><td>262121000210102</td><td>CNS toxicity</td></tr><tr><td>14760008</td><td>Constipation</td></tr><tr><td>414029004</td><td>Immune system disorder</td></tr><tr><td>262111000210107</td><td>Adjusted body weight calculation</td></tr><tr><td>262101000210105</td><td>Dose rounding</td></tr><tr><td>424122007</td><td>ECOG performance status finding</td></tr><tr><td>105593004</td><td>Electrolyte imbalance</td></tr><tr><td>106176003</td><td>Endocrine finding</td></tr><tr><td>248279007</td><td>Frailty</td></tr><tr><td>106028002</td><td>Musculoskeletal finding</td></tr><tr><td>165517008</td><td>Neutropenia</td></tr><tr><td>49808004</td><td>Advanced age</td></tr><tr><td>74964007</td><td>Other</td></tr><tr><td>407566003</td><td>Patient on maximum tolerated dose</td></tr><tr><td>302226006</td><td>Peripheral neuropathy</td></tr><tr><td>302215000</td><td>Thrombocytopenia</td></tr><tr><td>365921005</td><td>Weight change finding</td></tr></table></li></ul></div>"^^rdf:XMLLiteral
  ] ; # 
  fhir:url [ fhir:v "https://nzhts.digital.health.nz/fhir/ValueSet/canshare-sact-dose-adjustment-reason"^^xsd:anyURI] ; # 
  fhir:version [ fhir:v "0.5.0"] ; # 
  fhir:name [ fhir:v "DoseAdjustmentReason"] ; # 
  fhir:title [ fhir:v "Dose adjustment reason"] ; # 
  fhir:status [ fhir:v "draft"] ; # 
  fhir:experimental [ fhir:v false] ; # 
  fhir:date [ fhir:v "2026-06-15T22:18:26+00:00"^^xsd:dateTime] ; # 
  fhir:publisher [ fhir:v "Te aho o te kahu - Cancer Control Agency"] ; # 
  fhir:contact ( [
fhir:name [ fhir:v "Te aho o te kahu - Cancer Control Agency" ] ;
    ( fhir:telecom [
fhir:system [ fhir:v "email" ] ;
fhir:value [ fhir:v "mailto:david.hay25@gmail.com" ]     ] )
  ] ) ; # 
  fhir:description [ fhir:v "Reasons for adjusting the dose of a systemic anti-cancer therapy (SACT) treatment cycle plus other value."] ; # 
  fhir:jurisdiction ( [
    ( fhir:coding [
fhir:system [ fhir:v "urn:iso:std:iso:3166"^^xsd:anyURI ] ;
fhir:code [ fhir:v "NZ" ] ;
fhir:display [ fhir:v "New Zealand" ]     ] )
  ] ) ; # 
  fhir:compose [
    ( fhir:include [
fhir:system [ fhir:v "http://snomed.info/sct/21000210109"^^xsd:anyURI ] ;
      ( fhir:concept [
fhir:code [ fhir:v "271737000" ] ;
fhir:display [ fhir:v "Anaemia" ]       ] [
fhir:code [ fhir:v "262121000210102" ] ;
fhir:display [ fhir:v "CNS toxicity" ]       ] [
fhir:code [ fhir:v "14760008" ] ;
fhir:display [ fhir:v "Constipation" ]       ] [
fhir:code [ fhir:v "414029004" ] ;
fhir:display [ fhir:v "Immune system disorder" ]       ] [
fhir:code [ fhir:v "262111000210107" ] ;
fhir:display [ fhir:v "Adjusted body weight calculation" ]       ] [
fhir:code [ fhir:v "262101000210105" ] ;
fhir:display [ fhir:v "Dose rounding" ]       ] [
fhir:code [ fhir:v "424122007" ] ;
fhir:display [ fhir:v "ECOG performance status finding" ]       ] [
fhir:code [ fhir:v "105593004" ] ;
fhir:display [ fhir:v "Electrolyte imbalance" ]       ] [
fhir:code [ fhir:v "106176003" ] ;
fhir:display [ fhir:v "Endocrine finding" ]       ] [
fhir:code [ fhir:v "248279007" ] ;
fhir:display [ fhir:v "Frailty" ]       ] [
fhir:code [ fhir:v "106028002" ] ;
fhir:display [ fhir:v "Musculoskeletal finding" ]       ] [
fhir:code [ fhir:v "165517008" ] ;
fhir:display [ fhir:v "Neutropenia" ]       ] [
fhir:code [ fhir:v "49808004" ] ;
fhir:display [ fhir:v "Advanced age" ]       ] [
fhir:code [ fhir:v "74964007" ] ;
fhir:display [ fhir:v "Other" ]       ] [
fhir:code [ fhir:v "407566003" ] ;
fhir:display [ fhir:v "Patient on maximum tolerated dose" ]       ] [
fhir:code [ fhir:v "302226006" ] ;
fhir:display [ fhir:v "Peripheral neuropathy" ]       ] [
fhir:code [ fhir:v "302215000" ] ;
fhir:display [ fhir:v "Thrombocytopenia" ]       ] [
fhir:code [ fhir:v "365921005" ] ;
fhir:display [ fhir:v "Weight change finding" ]       ] )     ] )
  ] . #