{
  "resourceType" : "ValueSet",
  "id" : "an-dose-adjustment-reason",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet an-dose-adjustment-reason</b></p><a name=\"an-dose-adjustment-reason\"> </a><a name=\"hcan-dose-adjustment-reason\"> </a><ul><li>Include these codes as defined in <code>http://snomed.info/sct/21000210109</code><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td>271737000</td><td>Anaemia</td></tr><tr><td>262121000210102</td><td>CNS toxicity</td></tr><tr><td>14760008</td><td>Constipation</td></tr><tr><td>414029004</td><td>Immune system disorder</td></tr><tr><td>262111000210107</td><td>Adjusted body weight calculation</td></tr><tr><td>262101000210105</td><td>Dose rounding</td></tr><tr><td>424122007</td><td>ECOG performance status finding</td></tr><tr><td>105593004</td><td>Electrolyte imbalance</td></tr><tr><td>106176003</td><td>Endocrine finding</td></tr><tr><td>248279007</td><td>Frailty</td></tr><tr><td>106028002</td><td>Musculoskeletal finding</td></tr><tr><td>165517008</td><td>Neutropenia</td></tr><tr><td>49808004</td><td>Advanced age</td></tr><tr><td>74964007</td><td>Other</td></tr><tr><td>407566003</td><td>Patient on maximum tolerated dose</td></tr><tr><td>302226006</td><td>Peripheral neuropathy</td></tr><tr><td>302215000</td><td>Thrombocytopenia</td></tr><tr><td>365921005</td><td>Weight change finding</td></tr></table></li></ul></div>"
  },
  "url" : "https://nzhts.digital.health.nz/fhir/ValueSet/canshare-sact-dose-adjustment-reason",
  "version" : "0.5.0",
  "name" : "DoseAdjustmentReason",
  "title" : "Dose adjustment reason",
  "status" : "draft",
  "experimental" : false,
  "date" : "2026-06-15T22:18:26+00:00",
  "publisher" : "Te aho o te kahu - Cancer Control Agency",
  "contact" : [{
    "name" : "Te aho o te kahu - Cancer Control Agency",
    "telecom" : [{
      "system" : "email",
      "value" : "mailto:david.hay25@gmail.com"
    }]
  }],
  "description" : "Reasons for adjusting the dose of a systemic anti-cancer therapy (SACT) treatment cycle plus other value.",
  "jurisdiction" : [{
    "coding" : [{
      "system" : "urn:iso:std:iso:3166",
      "code" : "NZ",
      "display" : "New Zealand"
    }]
  }],
  "compose" : {
    "include" : [{
      "system" : "http://snomed.info/sct/21000210109",
      "concept" : [{
        "code" : "271737000",
        "display" : "Anaemia"
      },
      {
        "code" : "262121000210102",
        "display" : "CNS toxicity"
      },
      {
        "code" : "14760008",
        "display" : "Constipation"
      },
      {
        "code" : "414029004",
        "display" : "Immune system disorder"
      },
      {
        "code" : "262111000210107",
        "display" : "Adjusted body weight calculation"
      },
      {
        "code" : "262101000210105",
        "display" : "Dose rounding"
      },
      {
        "code" : "424122007",
        "display" : "ECOG performance status finding"
      },
      {
        "code" : "105593004",
        "display" : "Electrolyte imbalance"
      },
      {
        "code" : "106176003",
        "display" : "Endocrine finding"
      },
      {
        "code" : "248279007",
        "display" : "Frailty"
      },
      {
        "code" : "106028002",
        "display" : "Musculoskeletal finding"
      },
      {
        "code" : "165517008",
        "display" : "Neutropenia"
      },
      {
        "code" : "49808004",
        "display" : "Advanced age"
      },
      {
        "code" : "74964007",
        "display" : "Other"
      },
      {
        "code" : "407566003",
        "display" : "Patient on maximum tolerated dose"
      },
      {
        "code" : "302226006",
        "display" : "Peripheral neuropathy"
      },
      {
        "code" : "302215000",
        "display" : "Thrombocytopenia"
      },
      {
        "code" : "365921005",
        "display" : "Weight change finding"
      }]
    }]
  }
}